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Papillary renal carcinoma: Diagnostic approach by chemical shift gradient‐echo and echo‐planar MR imaging
Author(s) -
Yoshimitsu Kengo,
Kakihara Daisuke,
Irie Hiroyuki,
Tajima Tsuyoshi,
Nishie Akihiro,
Asayama Yoshiki,
Hirakawa Masakazu,
Nakayama Tomohiro,
Naito Seiji,
Honda Hiroshi
Publication year - 2006
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20509
Subject(s) - medicine , necrosis , echo (communications protocol) , hemosiderin , magnetic resonance imaging , radiology , nuclear medicine , renal cell carcinoma , gradient echo , pathology , computer network , computer science
Purpose To elucidate whether MRI can detect fat in interstitial histiocytes and hemosiderin (Hs) deposition (both of which are histological characteristics of papillary renal carcinoma (RCpap)) within RCpap. Materials and Methods Preoperative MR images of nine surgically confirmed RCpap and 57 clear cell renal carcinoma (RCcc) cases were retrospectively studied. Solid components of the lesions were evaluated. For fat detection, signal reduction on opposed‐phase images of chemical shift MRI (CSI) was used. For Hs detection, signal reduction on echo‐planar images or in‐phase images of CSI was used. The prevalence of fat and Hs detection was compared between RCpap and RCcc. Results In five of nine RCpap (54%), and 38 of 57 RCcc (67%), the presence of fat within the tumor was suggested by CSI ( P = 0.71). Hs deposition within tumors was suggested by either EPI or CSI in nine of nine RCpap (100%), and 28 of 57 RCcc (51%) ( P = 0.0036). Hs in RCpap was observed without or apart from necrosis or hemorrhage, whereas Hs in RCcc was located predominantly around necrosis. Conclusion Detecting intratumoral Hs by EPI or CSI, particularly that unrelated to necrosis or hemorrhage, may help differentiate RCpap from RCcc. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.