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Multicontrast delayed enhancement provides improved contrast between myocardial infarction and blood pool
Author(s) -
Kellman Peter,
Chung YiuCho,
Simonetti Orlando P.,
McVeigh Elliot R.,
Arai Andrew E.
Publication year - 2005
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20426
Subject(s) - medicine , contrast (vision) , myocardial infarction , nuclear medicine , contrast enhancement , cardiology , radiology , magnetic resonance imaging , artificial intelligence , computer science
Purpose To develop and test a delayed‐enhancement imaging method for improving the contrast between myocardial infarction (MI) and blood pool. Materials and Methods The T 2 of blood is significantly longer than that of acute or chronic MI. The proposed multicontrast delayed‐enhancement (MCODE) imaging method produces a series of images with both T 1 and T 2 weightings, which provides both excellent contrast between normal and infarcted myocardium, and between blood and MI. Results The subendocardial border between MI and blood pool was easily discriminated in the T 2 ‐weighted image. The measured MI‐to‐blood contrast‐to‐noise ratio (CNR) was better in the T 2 ‐weighted image than in the T 1 ‐weighted image (22.5 ± 8.7 vs. 2.9 ± 3.1, mean ± SD, N = 11, P < 0.001, for TrueFISP, and 19.4 ± 10.8 vs. 3.9 ± 2.3, N = 11, P < 0.001, for TurboFLASH). Conclusion The MCODE method provides a significant improvement in the ability to easily discriminate subendocardial MI by providing a T 2 ‐weighted image with high contrast between blood and MI. MCODE should improve both the detection and accurate sizing of MI. J. Magn. Reson. Imaging 2005. Published by Wiley‐Liss, Inc.