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Diffusion‐weighted images of the liver: Comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide
Author(s) -
Naganawa Shinji,
Sato Chiho,
Nakamura Tatsuya,
Kumada Hisashi,
Ishigaki Takeo,
Miura Shunichi,
Maruyama Katsuya,
Takizawa Osamu
Publication year - 2005
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20346
Subject(s) - medicine , contrast (vision) , diffusion mri , spleen , nuclear medicine , radiology , magnetic resonance imaging , maximum intensity projection , angiography , physics , optics
Purpose To study the recognition of malignant lesions of the liver on diffusion‐weighted images (DWI) can be improved by the administration of superparamagnetic iron oxide (SPIO). Materials and Methods Pre‐ and post‐SPIO mediated DWI of the liver was compared in six patients with suspected malignant liver lesions at 1.5 Tesla using a parallel imaging technique. Results Post‐SPIO DWI showed improved contrast‐to‐noise ratio between malignant lesions and liver. Furthermore, the spleen signal was decreased on post‐SPIO DWI, thus avoiding the overlap of the spleen and left lobe of the liver on maximum intensity projections (MIP). Conclusion Recognition of malignant lesions of the liver was improved by SPIO on DWI. On MIP images of DWI, SPIO helped to decrease the overlap of spleen signal on the liver in some projection angles. J. Magn. Reson. Imaging 2005;21:836–840. © 2005 Wiley‐Liss, Inc.