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T1 mapping of the entire lung parenchyma: Influence of the respiratory phase in healthy individuals
Author(s) -
Stadler Alfred,
Jakob Peter M.,
Griswold Mark,
Barth Markus,
Bankier Alexander A.
Publication year - 2005
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20319
Subject(s) - expiration , coronal plane , medicine , lung , nuclear medicine , significant difference , coefficient of variation , respiratory system , radiology , mathematics , anatomy , statistics
Purpose To determine the effect of respiratory phase on the T1 values of the entire lung. Materials and Methods We calculated T1 relaxation time on a pixel‐by‐pixel analysis of a series of Snapshot FLASH tomograms acquired after a single inversion pulse. Two sets of coronal T1 maps were acquired, one in full suspended inspiration and one in suspended expiration. Results The average of the mean T1 values over the entire lung in inspiration was 1199 ± 117 msec, the average of the mean T1 values in expiration was 1333 ± 167 msec. This difference was statistically significant, at P = 0.005. In inspiration the average coefficient of variation was 182 ± 56 msec, in expiration it was 153 ± 41 msec. This difference was not statistically significant. Conclusion T1 measurements of the entire lung are feasible. Our findings underline the need for a close monitoring of the inspirational status during MR examinations of the thorax, notably when T1 measurements of the lung are performed. J. Magn. Reson. Imaging 2005;21:759–764. © 2005 Wiley‐Liss, Inc.