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Feasibility of aortic pulse pressure and pressure wave velocity MRI measurement in young adults
Author(s) -
Laffon Eric,
Marthan Roger,
Montaudon Michel,
Latrabe Valérie,
Laurent François,
Ducassou Dominique
Publication year - 2005
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20227
Subject(s) - pulse wave velocity , pulse pressure , medicine , pulse (music) , pulse wave analysis , cardiology , blood pressure , acoustics , biomedical engineering , physics , optics , detector
Purpose To investigate the feasibility of assessing, noninvasively, aortic pulse pressure (APP) and pulse wave velocity (PWV) in the ascending aorta of young adults by means of velocity‐encoded magnetic resonance (MR) imaging. Materials and Methods In a series of 11 healthy volunteers, velocity‐encoded MR imaging provided pairs of magnitude and phase‐contrast images. Blood flow velocity and aortic cross‐sectional area (CSA) were determined with a 30‐msec temporal resolution. A model analysis revealed that variation in aortic CSA and in maximal blood flow velocity throughout systole could be used to estimate APP and, hence, to derive PWV by means of two different methods. Results Mean ± SD values of the APP for the series were 54.2 ± 16.4 mmHg (range 32.2–84.1 mmHg). The ascending aortic PWV mean ± SD values were 5.03 ± 1.10 m/second and 5.37 ± 1.23 m/second according to the two methods, and both estimates were not significantly different (95% confidence level). Conclusion These results are in agreement with previously published data, suggesting that APP and PWV can be determined, noninvasively, in young adults using MRI. J. Magn. Reson. Imaging 2005;21:53–58. © 2004 Wiley‐Liss, Inc.