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Single‐shot diffusion‐weighted RARE sequence: Application for temperature monitoring during hyperthermia session
Author(s) -
II′yasov Kamil A.,
Prof Jürgen Hennig
Publication year - 1998
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880080617
Subject(s) - diffusion , materials science , nuclear magnetic resonance , relaxation (psychology) , biomedical engineering , temperature gradient , repeatability , nuclear medicine , chemistry , physics , medicine , chromatography , thermodynamics , quantum mechanics
A diffusion‐sensitive single‐shot RARE (rapid acquisition with relaxation enhancement) sequence was implemented on a 2T whole‐body MRI system. The sequence was optimized for diffusion‐based MR thermometry, both on a conventional whole‐body gradient system and on a high‐performance gradient insert. The use of spin‐echo versus stimulated‐echo diffusion weighting is discussed as a function of gradient performance. Diffusion‐based temperature mapping was used to observe the effect of the geometry of the antenna used for radiofrequency (RF) hyperthermia on the temperature distribution. Temperature changes of ±.5°C in gel and ±2°C in a muscle sample in vitro could be detected within 16 seconds (gel) or 1 minute (muscle) at a spatial resolution of 2 × 2 × 8 mm. Temperature changes in vivo were also observed on human muscle cooled with ice with comparable sensitivity for the measured apparent diffusion coefficient (ADC) values.