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In vivo 1 H MRS of normal breast and breast tumors using a dedicated double breast coil
Author(s) -
Gribbestad Ingrid S.,
Singstad Trond E.,
Nilsen Gunnar,
Fjøsne Hans E.,
Engan Terje,
Haugen Olav A.,
Rinck Peter A.
Publication year - 1998
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880080602
Subject(s) - in vivo , breast tumor , breast cancer , choline , medicine , in vivo magnetic resonance spectroscopy , breast tissue , pathology , nuclear medicine , magnetic resonance imaging , nuclear magnetic resonance , radiology , cancer , biology , physics , microbiology and biotechnology
Image‐guided localized proton MR spectroscopy (MRS) of normal breasts and breast tumors (ductal and undifferentiated carcinomas) was performed using a dedicated double breast coil. In vivo 1 H MR spectra from 10 normal volunteers showed signals from water and lipids only, even in breasts with small contribution of fatty breast tissue. In the spectra from 6 of the 12 examined patients, an intense signal assigned to choline compounds was detected. The signal was also detected at lower levels in the remaining patients. This study shows that in vivo 1 H MRI/MRS examinations of breast tumors can be performed within an examination time of 45 to 60 minutes. Signals from breast tumor metabolites may be detected using in vivo 1 H MRS.