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Monitoring and visualization techniques for MR‐guided laser ablations in an open MR system
Author(s) -
Kettenbach Joachim,
Silverman Stuart G.,
Hata Nobuhiko,
Kuroda Kagayaki,
Saiviroonporn Pairash,
Zientara Gary P.,
Morrison Paul R.,
Hushek Stephen G.,
Black Peter McL.,
Kikinis Ron,
Jolesz Ferenc A.
Publication year - 1998
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880080424
Subject(s) - visualization , medicine , radiology , computer science , medical physics , nuclear medicine , artificial intelligence
Our purpose was to develop temperature‐sensitive MR sequences and image‐processing techniques to assess their potential of monitoring interstitial laser therapy (ILT) in brain tumors (n = 3) and liver tumors (n = 7). ILT lasted 2 to 26 minutes, whereas images from T1‐weighted fast‐spin‐echo (FSE) or spoiled gradient‐recalled (SPGR) sequences were acquired within 5 to 13 seconds. Pixel subtraction and visualization of T1‐weighted images or optical flow computation was done within less than 110 msec. Alternating phase‐mapping of real and imaginary components of SPGR sequences was performed within 220 msec. Pixel subtraction of T1‐weighted images identified thermal changes in liver and brain tumors but could not evaluate the temperature values as chemical shift‐based imaging, which was, however, more affected by susceptibility effects and motion. Optical flow computation displayed the predicted course of thermal changes and revealed that the rate of heat deposition can be anisotropic, which may be related to heterogeneous tumor structure and/or vascularization.