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Interleaved gradient echo planar (IGEPI) and phase contrast CINE‐PC flow measurements in the renal artery
Author(s) -
Bock Michael,
Schoenberg Stefan O.,
Schad Lothar R.,
Knopp Michael V.,
Essig Marco,
van Kaick Gerhard
Publication year - 1998
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880080419
Subject(s) - medicine , renal artery , stenosis , phase contrast microscopy , artery , blood flow , nuclear medicine , temporal resolution , radiology , kidney , cardiology , physics , optics
ECG‐gated phase contrast (CINE‐PC) flow measurements in the renal artery help to differentiate between low‐ and high‐grade stenoses. Because conventional CINE‐PC acquisitions with high temporal resolution require acquisition times of several minutes, respiratory motion results in a systematic overestimation of renal artery flow. With the use of an interleaved gradient echo‐planar technique (IGEPI), total measurement times can be shortened to about 30 seconds, while a high spatial and temporal resolution is maintained. In this study, an IGEPI CINE‐PC flow measurement pulse sequence with 16 gradient echoes was compared with a non‐breathheld conventional CINE‐PC technique. Flow‐time curves were measured in volunteers and in patients with suspected renal artery stenosis. With IGEPI CINE‐PC, mean flow velocity, vessel cross‐sectional area, and mean blood flow were substantially lower by 9% to 25%. Contrast‐enhanced 3D MR angiography was used to compare stenosis grading based on flow‐time curve patterns with morphologic grading. With IGEPI CINE‐PC, all high‐grade stenoses (n = 5) were detected, whereas only 66% (n = 3) were found with conventional CINE‐PC.