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Variations in blood flow waveforms in stenotic renal arteries by 2D phase‐contrast cine MRI
Author(s) -
Westenberg Jos J. M.,
Wasser Martin N. J. M.,
van der Geest Rob J.,
Pattynama Peter M. T.,
de Roos Albert,
Vanderschoot Jan,
Reiber Johan H. C.
Publication year - 1998
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880080312
Subject(s) - medicine , stenosis , cardiology , digital subtraction angiography , blood flow , diastole , blood pressure , hemodynamics , subtraction , radiology , angiography , arithmetic , mathematics
Waveform variations in blood flow measurements through stenotic renal arteries have been reported already with echo Doppler studies. We studied these variations with MRI in 14 patients (mean age, 60 years) with suspected renal arterial stenosis (24 patent arteries, four occluded). Flow measurements were successful in 15 arteries and unsuccessful in nine, due to practical limitations. Seven healthy younger volunteers (mean age, 28 years) and five healthy older volunteers (mean age, 58 years) were recruited for comparison purposes. In patients, the severity of stenoses was also assessed by digital subtraction angiography and intraarterially measured transstenotic pressure drops. We found flow patterns to be statistically significantly ( P < 0.01) age‐related. Younger healthy subjects showed shorter wave duration, higher diastolic flow, and total blood flow per minute. Also, with increasing stenosis severity, the systolic wave became more damped and the systolic wave duration became statistically significantly ( P > = .03) longer.