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Multi‐echo 31 P spectroscopic imaging of ATP: A scan time reduction strategy
Author(s) -
Chao Hui,
Bowers John L.,
Holtzman David,
Mulkern Robert V.
Publication year - 1997
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880070229
Subject(s) - echo (communications protocol) , nuclear magnetic resonance , reduction (mathematics) , coupling (piping) , adenosine triphosphate , physics , spin echo , chemistry , magnetic resonance imaging , computer science , materials science , medicine , mathematics , radiology , biochemistry , computer network , geometry , metallurgy
Spectroscopic imaging of 31 P metabolites and adenosine triphosphate (ATP) in particular with multiple spin echoes may prove useful for reducing data acquisition times. The usual T2 decay processes that degrade multi‐echo spectroscopic imaging methods, however, are further compounded by J ‐coupling modulations in the case of ATP. We determine how these modulations affect multi‐echo spectroscopic imaging k‐space data and produce systematic spatial misregistrations of the ATP resonances. The specific J ‐coupling modulations of ATP are determined to identify echo‐spacing effects in multi‐echo spectroscopic imaging of ATP and to determine appropriate post‐processing correction schemes to address the spatial misregistration problem. An in vivo demonstration of the technique that offers a threefold reduction in scan time compared to conventional SI methods is provided and compared with the conventional SI approach.