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Contrast‐enhanced MR imaging in the evaluation of treatment response and prediction of outcome in multiple sclerosis
Author(s) -
Simon Jack H.
Publication year - 1997
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880070106
Subject(s) - multiple sclerosis , subclinical infection , medicine , neuroimaging , contrast (vision) , magnetic resonance imaging , disease , radiology , pathology , computer science , artificial intelligence , psychiatry
MR imaging is becoming increasingly important in the evaluation of multiple sclerosis based on its sensitivity to acute, often subclinical events in the brain and because it provides a basis for measuring the accumulation of disease over time. Contrast‐enhanced MR imaging in particular evaluates disease at the fundamental level of events affecting the blood‐brain barrier. This review emphasizes ( a ) recent developments in the use of contrast‐enhanced MR imaging as a measure of disease in patient groups and individuals and ( b ) its emerging role in evaluating new therapies.