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Multislice T1‐weighted hybrid rare in CNS imaging: Assessment of magnetization transfer effects and artifacts
Author(s) -
Melhem Elias R.,
Jara Hernan,
Yucel E. Kent
Publication year - 1996
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880060611
Subject(s) - magnetization transfer , nuclear magnetic resonance , multislice , white matter , physics , magnetic resonance imaging , spin echo , magnetization , computer science , medicine , radiology , quantum mechanics , magnetic field
Using a T1‐weighted hybrid rapid acquisition with relaxation enhancement (RARE) MR sequence that implements an echo‐to‐view mapping scheme termed “low‐high profile order,” we evaluated signal intensity changes in different brain tissues as a function of number of slices, interslice gap, and echo train length (ETL). We also measured phase‐encode and frequency‐encode noise as well as blurring artifacts along the phase‐encode direction as a function of ETL. Off‐resonance magnetization transfer effects were demonstrated to be responsible for signal intensities changes in white matter and gray matter when using multislice techniques. These effects are amplified by increasing the number of slices and ETL. Due to the nature of the implemented echo‐to‐view mapping scheme, no on‐resonance magnetization transfer effects were observed from the intraslice echo train. Selective background (white matter and gray matter) suppression in multislice T1‐weighted hybrid RARE, secondary to off‐resonance magnetization transfer effects, may provide better contrast resolution of enhancing central nervous system (CNS) lesions at much shorter scan time as compared to conventional spin‐echo T1‐weighted sequences. This improvement in contrast resolution as a function of ETL may be limited by worsening phase‐encode noise and blurring artifacts.