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Functional MRI in human somatosensory cortex activated by touching textured surfaces
Author(s) -
Lin Weili,
Kuppusamy Karthikeyan,
Haacke E. Mark,
Burton Harold
Publication year - 1996
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880060402
Subject(s) - somatosensory system , central sulcus , sensory stimulation therapy , functional magnetic resonance imaging , cortex (anatomy) , stimulation , neuroscience , sensory system , sulcus , sensory cortex , motor cortex , anatomy , medicine , psychology
MRI revealed activation foci in human somatosensory cortex during protocols involving stimulation of the fingertips with a textured surface. A 2D T2*‐weighted gradient echo sequence was used to acquire images. The imaging protocol included acquiring images while subjects performed specific tactile stimulation paradigms (activation scans) or rested. Three different paradigms were used to produce functional activation using a textured surface to rub the fingertips of one hand. First, motor sensory activation was produced by rubbing the textured surface held in one hand against the fingertips of the opposite hand only during the activation scans. Second, the hand holding the textured surface moved throughout the experiment but touched the fingertips of the opposite hand only during the activation scans. Third, subjects remained still in the magnet throughout the entire study while an investigator rubbed the textured surface against the subjects' fingertips during the activation scans. Images were postprocessed using a cross‐correlation scheme. The results revealed multiple foci of motor sensory activation near the central sulcus, postcentral sulcus, and prefrontal cortex.