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Fast spin‐echo characteristics of visual stimulation‐induced signal changes in the human brain
Author(s) -
Gao JiaHong,
Xiong Jinhu,
Li Jinqi,
Schiff Joseph,
Roby John,
Lancaster Jack L.,
Fox Peter T.
Publication year - 1995
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880050615
Subject(s) - visual cortex , human brain , signal (programming language) , neuroscience , brain activity and meditation , nuclear magnetic resonance , functional imaging , spin echo , computer science , biomedical engineering , medicine , magnetic resonance imaging , physics , electroencephalography , psychology , radiology , programming language
A fast spin‐echo (FSE) technique used in a conventional MR imaging scanner has been successfully developed for obtaining functional MR images with high spatial resolution and multiple slices. Our preliminary visual stimulation studies using the FSE technique show that the nuclear MR signal increases by 2.6% during activation in the primary visual cortex. These results provide evidence that the diffusion of tissue water molecules plays a key role in determining functional MR signal amplitude. Because the FSE functional MR imaging signal is extremely sensitive to microvascular (brain capillaries) hemodynamics, the FSE technique can be a powerful tool for studying the neuronal activity of the human brain.