Premium
Effects of MR exposure on akonal outgrowth in the sympathetic nervous system of the chick
Author(s) -
Yip Yee Ping,
Capriotti Christine,
W. Y Joseph
Publication year - 1995
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880050416
Subject(s) - fibronectin , extracellular matrix , embryo , sympathetic nervous system , central nervous system , anatomy , matrix (chemical analysis) , extracellular , significant difference , biology , pathology , chemistry , microbiology and biotechnology , neuroscience , medicine , endocrinology , chromatography , blood pressure
The effects of MR exposure on the rate and specificlty of sympathetic preganglionic axonal outgrowth were examined in the chick embryo. Embryos were exposed to a static magnetic field of 1.5 T for 6 hours, 64 MHt RF field pulses, and a Switched magnetic field gradient of amplitude 0.6 G/cm for 4 hours. No significant difference in axonal outgrowth wm observed between MR‐exposed and control embryos. In addition. the distributionr of several major extracellular matrix (ECM) molecules, lpmlnln, fibronectin, and collagen N, were examined. Immunoetaining patterns of these ECM molecules duxing axonal outgrowth showed no difference between MR‐expored and control embryos. Our results suggert that the MR erporure conditions used in this study do not affect axonal outgrowth in the sympathetic nervous system of the chick.