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Dynamic MR mammography: A technique for potentially reducing the biopsy rate for benign breast disease
Author(s) -
Turkat Terry J.,
Klein Barry D.,
Polan Ruth L.,
Richman Roselyn H.
Publication year - 1994
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880040409
Subject(s) - medicine , mammography , biopsy , radiology , magnetic resonance imaging , breast cancer , breast disease , nuclear medicine , cancer
Thirty‐five women with a total of 39 breast lesions detected at mammography and/or physical examination and who were scheduled for surgical biopsy were studied with dynamic magnetic resonance (MR) mammography. Fat‐suppressed, spoiled GRASS (gradient‐recalled acquisition in the steady state) sequences were performed before and after administration of gadopentetate dimeglumine. T1‐weighted spin‐echo and fat‐suppressed T2‐weighted fast spin‐echo images were also obtained. By measuring percentage signal intensity change in lesions on the spoiled GRASS images after contrast agent injection, the authors achieved a sensitivity of 100% and a specificity of 83.3% in differentiating benign from malignant lesions (24 benign, 15 malignant), with biopsy results as the standard. This dynamic MR mammography technique deserves further evaluation.