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Susceptibility effects in porous media in the presence of flow
Author(s) -
Su MinYing,
Nalcioglu Orhan
Publication year - 1993
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880030516
Subject(s) - imaging phantom , materials science , intensity (physics) , porous medium , spins , magnetic resonance imaging , nuclear magnetic resonance , magnetic field , flow (mathematics) , magnetic susceptibility , bead , signal (programming language) , porosity , biomedical engineering , mechanics , optics , physics , composite material , condensed matter physics , radiology , computer science , medicine , quantum mechanics , programming language
Magnetic resonance (MR) imaging of microvascular flow is an important topic in biomedicine because it permits access to the functional state of a biologic system. The internal heterogeneous magnetic field due to susceptibility differences within tissues is one of the factors that can affect signal intensity. A glass bead phantom simulating a porous medium was used to experimentally study the effect of the internal magnetic field on MR flow measurements. A physical model was developed to simulate the paths of the moving spins and the local magnetic field distribution in the medium to estimate the signal intensity with spin‐phase analysis. The susceptibility variation inside the glass bead phantom was estimated by comparing the simulation results with the experimental data. Experiments were also performed with a tissue‐simulating phantom, and the results indicated that the effect of the internal field inhomogeneity on in vivo microvascular flow measurements was negligible.