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Correlation of cine MR velocity measurements in the internal carotid artery with collateral flow in the circle of willis: Preliminary study
Author(s) -
Davis Wayne L.,
Turski Patrick A.,
Gorbatenko Kristina G.,
Weber David
Publication year - 1993
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880030409
Subject(s) - circle of willis , medicine , stenosis , internal carotid artery , magnetic resonance angiography , radiology , magnetic resonance imaging , anterior cerebral artery , phase contrast microscopy , angiography , anterior communicating artery , hemodynamics , collateral circulation , cardiology , middle cerebral artery , ischemia , aneurysm , physics , optics
Abstract The velocity‐phase relationship intrinsic to phase‐contrast magnetic resonance (MR) angiography permits the quantitative and qualitative assessment of blood flow. The ability to measure velocity and vessel cross‐sectional area allows noninvasive assessment of volume flow rate (VFR) in the internal carotid artery (ICA). Phase‐contrast techniques also demonstrate flow direction. Using two‐dimensional cine phase‐contrast angiography, the authors evaluated VFR in the ICA and collateral flow about the circle of Willis in 15 patients with ischemic neurologic symptoms. The VFR in each carotid artery was correlated with the degree of stenosis and presence or absence of abnormal circle of Willis collateral flow. There was a correlation between a decrease in VFR and abnormal circle of Willis collateral flow. In addition, a correlation between severe stenosis and a decrease in VFR was found. In patients with ischemic neurologic symptoms without severe stenosis (<70% diameter stenosis), no decrease in VFR was seen. It is hoped that flow quantification and directional flow imaging with phase‐contrast angiography will help further characterize carotid artery occlusive disease by enabling assessment of VFR changes associated with ischemic neurologic symptoms. This study also supports the hypothesis that two mechanisms‐hemodynamic and embolic‐play a role in ischemic neurologic symptoms.