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Quantitative analysis of gadopentetate dimeglumine excreted in breast milk
Author(s) -
Rofsky Neil M.,
Weinreb Jeffrey C.,
Litt Andrew W.
Publication year - 1993
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880030122
Subject(s) - medicine , nuclear medicine , radiology
Specimens of breast milk were obtained from each breast in a lactating patient for a 24‐hour period after a gadolinium‐enhanced MR imaging examination was performed. A quantitative analysis of gadolinium content in specimens obtained at 2, 11, 17, and 24 hours after the intravenous administration of gadopentetate dimeglumine demonstrated that gadolinium is excreted in small amounts (total of 1.60 μmol during a 24‐hour period) and in similar amounts from each breast. These results suggest that a waiting period of 24 hours, with active expression of breast milk from each breast, should provide a reasonable safety margin for allowing resumption of breast‐feeding. Additional data will be required before establishing definitive recommendations.