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Improved cine MR imaging of left ventricular wall motion with gadopentetate dimeglumine
Author(s) -
Pennell Dudley J.,
Richard Underwood S.,
Longmore Donald B.
Publication year - 1993
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1880030104
Subject(s) - short axis , medicine , long axis , magnetic resonance imaging , systole , contrast (vision) , diastole , nuclear medicine , cardiac cycle , contrast effect , cardiology , radiology , physics , blood pressure , mathematics , geometry , optics
The assessment of left ventricular wall motion with cine magnetic resonance imaging in the cardiac long axes is useful; however, image quality is limited by reduced signal intensity due to saturation of blood flowing predominantly in plane. Twenty subjects were studied to evaluate the effects of gado‐pentetate dimeglumine on contrast between blood and myocardium. Contrast improved significantly on contrast agent –‐ enhanced images in the long axes, at both end‐systole (vertical axis, +62%, P <.0001; horizontal axis, +67%, P <.0001) and end‐diastole (vertical axis, +50%,P <.0001; horizontal axis, +26%, P <.004). The increase in the short axis was less and significant only at end‐systole (+25%, P <.0001). Subjective scoring of the cines also showed a significant and clinically useful improvement in the long axes (P <.0001 for both) on contrast‐enhanced images. Improved contrast was most evident for 10 minutes after injection, but persisted for up to 20 minutes at end‐systole in the long axes. Gadopentetate dimeglumine is useful for cine imaging of left ventricular wall motion when saturation effects prevent adequate clinical assessment.