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MR renography by semiautomated image analysis: Performance in renal transplant recipients
Author(s) -
de Priester Jacobus A.,
Kessels Alphons G.H.,
Giele Eelco L.W,
den Boer Jacques A.,
Christiaans Maarten H.L.,
Hasman Arie,
van Engelshoven Jos M.A.
Publication year - 2001
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1163
Subject(s) - nuclear medicine , coronal plane , renal transplant , medicine , intraclass correlation , cortex (anatomy) , renal cortex , transplantation , kidney , radiology , surgery , biology , clinical psychology , neuroscience , psychometrics
We evaluated a method of semiautomated analysis of dynamic MR image series in renal transplants. Nine patients were studied twice, with an average time interval of 7 days. MR examination consisted of a run of 256 T1‐weighted coronal scans (GE; TR/TE/flip: = 11/3.4/60°; slice thickness = 6 mm; temporal resolution = 2 seconds). Gadolinium‐DTPA (0.05 mmol/kg) was injected with an injector pump (5 ml/seconds). MR renographs of the cortex and medulla were obtained by segmentation of the renal transplant and placement of two regions of interest (ROIs) overlying the peripheral and central renal parenchyma. In the first 100 frames of the renographs, analysis of variance (ANOVA) demonstrated significant intraclass correlation coefficients with mean values for the cortex and medulla of 0.47 and 0.59, respectively. We conclude that the procedure is a robust technique that generates meaningful signal curves. J. Magn. Reson. Imaging 2001;14:134–140. © 2001 Wiley‐Liss, Inc.