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Evaluation of female intrapelvic tumors by clinical proton MR spectroscopy
Author(s) -
Okada Toshiko,
Harada Masafumi,
Matsuzaki Kenji,
Nishitani Hiromu,
Aono Toshihiro
Publication year - 2001
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1130
Subject(s) - proton magnetic resonance , in vivo magnetic resonance spectroscopy , differential diagnosis , medicine , pelvis , pathology , magnetic resonance imaging , radiology , nuclear medicine , ovary , choline , nuclear magnetic resonance , physics
We measured metabolites in large tumors of the female pelvis (23 cases total: 6 malignant cases, 17 benign cases) using single‐voxel proton magnetic resonance (MR) spectroscopy and evaluated the clinical significance of this method in the differential diagnosis of female pelvic tumors. The characteristically obtained signal was lactate, which was detected not only in all the malignant tumors but also in some of the benign tumors. However, the lactate signals of the malignant tumors tended to form higher peaks than those of benign tumors, which was a finding consistent with the result of the earlier in vitro study reported in ovarian tumors. The signal of choline‐containing compounds (Cho) was found only in solid tumors, and the signal intensity varied among different histological types of tumors, possibly reflecting metabolic activity of the cell membrane. We considered that proton MR spectroscopy (MRS) of intrapelvic tumors would be useful for the diagnosis of the nature of female intrapelvic tumors. J. Magn. Reson. Imaging 2001;13:912–917. © 2001 Wiley‐Liss, Inc.