Fast  13 C‐glucose metabolite mapping in rat brain using  1 H echo planar spectroscopic imaging technique at 2T | Zendy

Morikawa Shigehiro | Zendy; Inubushi Toshiro | Zendy

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Fast 13 C‐glucose metabolite mapping in rat brain using 1 H echo planar spectroscopic imaging technique at 2T

Author(s) -

Morikawa Shigehiro,

Inubushi Toshiro

Publication year - 2001

Publication title -

journal of magnetic resonance imaging

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.563

H-Index - 160

eISSN - 1522-2586

pISSN - 1053-1807

DOI - 10.1002/jmri.1109

Subject(s) - nuclear magnetic resonance , metabolite , echo time , echo planar imaging , magnetic resonance spectroscopic imaging , chemistry , magnetic resonance imaging , nuclear magnetic resonance spectroscopy , nuclear medicine , physics , medicine , radiology , biochemistry

For fast 13 C metabolite mapping in rat brains, 1 H‐detected 13 C NMR spectroscopy using gradient‐enhanced heteronuclear multiple‐quantum coherence and 1 H echo planar spectroscopic imaging were combined. 13 C glucose and 3‐/4‐ 13 C‐Glu/Gln images of rat brain were successfully constructed with 35‐minute temporal resolution under a 2T magnetic field. In the ischemic region of the suture middle cerebral artery occlusion model, glucose and Glu/Gln signals decreased and lactate signals appeared. J. Magn. Reson. Imaging 2001;13:787–791. © 2001 Wiley‐Liss, Inc.

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