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Language dominance assessment by means of fMRI: Contributions from task design, performance, and stimulus modality
Author(s) -
HundGeorgiadis Margret,
Lex Ulrike,
von Cramon D. Yves
Publication year - 2001
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1094
Subject(s) - inferior frontal gyrus , modality (human–computer interaction) , functional imaging , cognitive psychology , psychology , stimulus (psychology) , lateralization of brain function , task (project management) , stimulus modality , audiology , laterality , modalities , perception , functional magnetic resonance imaging , neuroscience , computer science , medicine , artificial intelligence , social science , management , sociology , economics
We investigated the influence of different task demands, task designs, and presentation modalities on the functional MRI activation patterns during a language lateralization task in a group of 14 right‐handed control subjects. A word classification task was presented as target task appropriate to evoke language‐related activation in the inferior frontal gyrus (IFG). The choice of the contrasting baseline task was demonstrated to have a major impact on the functional outcome: While a fixation baseline elicited activations in the inferior frontal gyrus of both hemispheres, a nonsemantic perceptual control task helped to isolate the relevant target task of word classification. The modality of stimulus presentation did not influence the functional data: Auditory and visual presentation modes broadly evoked activations in similar brain regions during word classification. Minor differences in task performance and the side of the responding hand did not interfere with the functional activation patterns of the target task. On the basis of our results, a protocol of functional lateralization in the inferior frontal gyrus is suggested. J. Magn. Reson. Imaging 2001;13:668–675. © 2001 Wiley‐Liss, Inc.