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The effects of 1.5T magnetic resonance imaging on early murine in‐vitro embryo development
Author(s) -
Chew Stephen,
Ahmadi Ali,
Goh P.S.,
Foong L.C.
Publication year - 2001
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.1060
Subject(s) - blastocyst , magnetic resonance imaging , embryo , in vitro , embryogenesis , biology , nuclear magnetic resonance , andrology , medicine , microbiology and biotechnology , physics , radiology , genetics
Although no ionizing radiation is involved, patients undergoing magnetic resonance imaging (MRI) are exposed to powerful static magnetic fields, magnetic field gradients, and radio‐frequency fields that may be potentially damaging. Our study aims to document the effect of MRI imaging sequences on early murine embryo development (two‐cell to blastocyst stage) in vitro. Two‐cell murine embryos were exposed to various lengths of MRI using pulse sequences employed in present day clinical imaging. Early murine embryo development was documented in vitro, and blastocyst development rates were computed for both the control and exposed groups. There were no significant differences detected in the rate of blastocyst formation between the control groups and the embryos exposed to MRI. J. Magn. Reson. Imaging 2001;13:417–420. © 2001 Wiley‐Liss, Inc.