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Biliary motor function in gallstone patients evaluated by fatty‐meal MR cholangiography
Author(s) -
Inoue Yusuke,
Komatsu Yutaka,
Yoshikawa Kohki,
Akahane Masaaki,
Isayama Hiroyuki,
Ohtomo Kuni,
Omata Masao
Publication year - 2003
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.10340
Subject(s) - postprandial , medicine , gallstones , gallbladder , gastroenterology , impaction , surgery , insulin
Purpose: To investigate the possibility of evaluating biliary motor function with magnetic resonance cholangiography (MRC). Materials and Methods: Twenty patients with gallstones and 30 control subjects were studied using fatty‐meal MRC. After baseline MRC, they were encouraged to drink 250 mL of milk and underwent postprandial MRC every 10 minutes for 60 minutes. Postprandial changes in gallbladder volume and the diameter of the common duct were assessed as indicators of gallbladder contractility and biliary obstruction, respectively. Postprandial dilatation at 60 minutes was considered indicative of persistent biliary obstruction. Results: Gallbladder ejection fraction was calculated at 66.0% ± 12.2% (range, 40.3%–88.6%) in the controls. Gallbladder volume expressed as a percentage of the baseline value was significantly larger at 20–60 minutes in the gallstone patients than in the controls. Gallbladder ejection fraction varied widely (mean, 46.4% ± 24.4%; range, 2.8%–81.5%) and was significantly reduced in comparison with that of the controls ( P < 0.01). In two gallstone patients with co‐existing ductal stones, transient postprandial dilatation associated with ampullary impaction was observed. Persistent biliary obstruction was not indicated in any subjects. Conclusion: The results of this study suggest the feasibility of fatty‐meal MRC, as well as its potential for evaluating biliary motor function. J. Magn. Reson. Imaging 2003;18:196–203. © 2003 Wiley‐Liss, Inc.