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MRI measurement of time‐resolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions
Author(s) -
Papathanasopoulou Panorea,
Zhao Shunzhi,
Köhler Uwe,
Robertson Malcolm B.,
Long Quan,
Hoskins Peter,
Yun Xu X.,
Marshall Ian
Publication year - 2003
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.10243
Subject(s) - computational fluid dynamics , mechanics , shear stress , pulsatile flow , inflow , bifurcation , carotid bifurcation , flow (mathematics) , imaging phantom , outflow , physics , materials science , biomedical engineering , carotid arteries , medicine , optics , nonlinear system , quantum mechanics , meteorology , cardiology
Abstract Purpose To study pulsatile fluid flow in a physiologically realistic model of the human carotid bifurcation, and to derive wall shear stress (WSS) vectors. Materials and Methods WSS vectors were calculated from time‐resolved 3D phase‐contrast (PC) MRI measurements of the velocity field. The technique was first validated with sinusoidal flow in a straight tube, and then used in a model of a healthy human carotid bifurcation. Velocity measurements in the inflow and outflow regions were also used as boundary conditions for computational fluid dynamics (CFD) calculations of WSS, which were compared with those derived from MRI alone. Results The straight tube measurements gave WSS results that were within 15% of the theoretical value. WSS results for the phantom showed the main features expected from fluid dynamics, notably the low values in the bulb region of the internal carotid artery, with a return to ordered flow further downstream. MRI was not able to detect the high WSS values along the divider wall that were predicted by the CFD model. Otherwise, there was good general agreement between MRI and CFD. Conclusion This is the first report of time‐resolved WSS vectors estimated from 3D‐MRI data. The technique worked well except in regions of disturbed flow, where the combination with CFD modeling is clearly advantageous. J. Magn. Reson. Imaging 2003;17:153–162. © 2003 Wiley‐Liss, Inc.