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Estimation of left ventricular performance through temporal pressure variations measured by MR velocity and acceleration mappings
Author(s) -
Tasu JeanPierre,
Mousseaux Elie,
Colin Patrice,
Slama Michel S.,
Jolivet Odile,
Bittoun Jacques
Publication year - 2002
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.10162
Subject(s) - pulsatile flow , acceleration , contractility , ascending aorta , cardiology , aorta , medicine , aortic pressure , imaging phantom , ventricular pressure , blood flow , ventricular function , biomedical engineering , nuclear magnetic resonance , nuclear medicine , physics , hemodynamics , classical mechanics
Abstract Purpose To describe a method for assessing pressure variation vs. time (dp/dt) using blood flow acceleration measured by MRI, and to demonstrate its applicability in estimating left ventricular (LV) function. Materials and Methods The method was tested in vitro using a pulsatile phantom, and a strong correlation was found between transducer and MRI determinations of dp/dt (r = 0.98). Selected aortic flow parameters were then measured in 10 patients and the results were compared with transducer measurements of the LV dp/dt. Results The correlation coefficients for the reference estimations of global myocardial function and MRI were 0.59 for aortic velocity, 0.74 for aortic acceleration, and 0.86 for aortic dp/dt. Conclusion MR measurements of velocity and acceleration within the ascending aorta offer a noninvasive method for determining indices, such as the aortic dp/dt, that are closely correlated with the global myocardial contractility function. J. Magn. Reson. Imaging 2002;16:246–252. © 2002 Wiley‐Liss, Inc.