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Optimal post‐contrast timing of breast MR image acquisition for architectural feature analysis
Author(s) -
Nunes Linda White,
Englander Sarah A.,
Charafeddine Riad,
Schnall Mitchell D.
Publication year - 2002
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.10135
Subject(s) - contrast (vision) , feature (linguistics) , magnetic resonance imaging , dynamic contrast , nuclear medicine , receiver operating characteristic , medicine , contrast effect , radiology , computer science , artificial intelligence , linguistics , philosophy
Purpose To define a post‐contrast imaging time span during which diagnostic accuracy of breast magnetic resonance (MR) architectural feature analysis is maintained. Materials and Methods Seventy‐five patients with mammographically‐visible or palpable findings underwent MR examination. Three sequential post‐contrast, fat‐saturated, three‐dimensional gradient‐echo imaging runs were acquired spanning 0–90, 90–180, and 180–270 seconds after contrast injection. Five readers independently predicted the malignant potential of the MR abnormalities. Results Receiver‐operator characteristics (ROC) curves were our primary measure of diagnostic accuracy. The accuracy of four readers was unchanged over the three post‐contrast runs. One reader was slightly more accurate using the second and third runs than using the first. Conclusion For most readers, a single post‐contrast run performed at any point during the first four minutes and 30 seconds following injection should yield an equivalent diagnostic accuracy. If any time period is less optimal, it is that of our first run, performed between 0–90 seconds after contrast injection. J. Magn. Reson. Imaging 2002;16:42–50. © 2002 Wiley‐Liss, Inc.