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Diffusion‐ and perfusion‐weighted MR imaging in a patient with acute demyelinating encephalomyelitis (ADEM)
Author(s) -
Bernarding Johannes,
Braun Jürgen,
Koennecke HansChristian
Publication year - 2002
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.10045
Subject(s) - medicine , perfusion , diffusion mri , acute disseminated encephalomyelitis , encephalomyelitis , magnetic resonance imaging , pathology , perfusion scanning , nuclear medicine , multiple sclerosis , radiology , psychiatry
To monitor changes of brain tissue metabolism in acute demyelinating encephalitis (ADEM), we examined a patient with suspected ADEM by serial MRI including diffusion‐ and perfusion‐weighted imaging (DWI, PWI). Within the inflammatory tissue, the apparent diffusion coefficients were reduced, normal, and increased. Perfusion varied between reduced and normal values, except for small hyperperfused regions. Combining standard MRI with DWI and PWI may elucidate different overlapping phases in cerebral inflammation. J. Magn. Reson. Imaging 2002;15:96–100. © 2002 Wiley‐Liss, Inc.