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Minimizing contrast agent dose during intraarterial gadolinium‐enhanced MR angiography: In vitro assessment
Author(s) -
Hwang KenPin,
Green Jordin D.,
Li Debiao,
Simonetti Orlando P.,
Resnick Scott A.,
Finn J. Paul,
Duerk Jeffrey L.,
Omary Reed A.
Publication year - 2002
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.10027
Subject(s) - gadolinium , medicine , magnetic resonance angiography , iliac artery , angiography , contrast (vision) , aorta , nuclear medicine , imaging phantom , magnetic resonance imaging , limiting , artery , blood flow , radiology , cardiology , materials science , artificial intelligence , computer science , metallurgy , mechanical engineering , engineering
Purpose To minimize contrast agent dosage for intra‐arterial (IA) contrast‐enhanced magnetic resonance angiography (CE‐MRA) by examining the effects of encoding order (elliptical vs. sequential) and injection duration (100% to 30% of the acquisition time). Materials and Methods Catheter‐based IA gadolinium (Gd) injections were performed in an arterial flow phantom. Blood flow rates, injection rates, and injection durations were systematically varied. Signal‐to‐noise (SNR) measurements were obtained in the aorta, renal artery, and common iliac artery. Results No significant SNR losses were observed for any of the vessels with 75% injection duration, or for the aorta and iliac artery with 50% injection duration. Excellent images of all vessels were obtained at 50% injection duration. There was no significant SNR difference between encoding schemes. Conclusion Contrast agent dosage can be substantially reduced without loss of SNR by limiting injection to part of the imaging acquisition time. J. Magn. Reson. Imaging 2002;15:55–61. © 2002 Wiley‐Liss, Inc.