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The molecular reaction vessels for a transesterification process created by molecular imprinting technique
Author(s) -
Meng Zihui,
Sode Koji
Publication year - 2005
Publication title -
journal of molecular recognition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.401
H-Index - 79
eISSN - 1099-1352
pISSN - 0952-3499
DOI - 10.1002/jmr.732
Subject(s) - transesterification , catalysis , chemistry , itaconic acid , molecular imprinting , polymerization , polymer chemistry , kinetics , enzyme kinetics , organic chemistry , nuclear chemistry , polymer , copolymer , selectivity , active site , physics , quantum mechanics
A polymeric catalyst was synthesized by co‐polymerizing 4(5)‐vinylimidazole and itaconic acid with trimethylpropanol trimethacrylate micro spheres. The catalyst obtained catalysed the transesterification process between p ‐nitrophenyl acetate and hexanol with maximal initial velocity(ν max ) of 4.73 ± 0.47 μ M min −1 mg −1 , and turnover rate ( k cat ) of 8.67 min −1 . Using p ‐nitrophenyl acetate as template, molecular imprinting process enhanced the ν max of the polymeric catalyst 3‐fold. Each imprinted site can be considered as a single molecular reaction vessel, and achieved a k cat of 169 min −1 towards the conversion of p ‐nitrophenyl acetate in hexanol. Copyright © 2004 John Wiley & Sons, Ltd.