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Pyrrole‐coupled salicylimine‐based fluorescence “turn on” probe for highly selective recognition of Zn 2+ ions in mixed aqueous media: Application in living cell imaging
Author(s) -
Bhosale Jitendra,
Fegade Umesh,
Bondhopadhyay Banashree,
Kaur Simanpreet,
Singh Narinder,
Basu Anupam,
Dabur Rajesh,
Bendre Ratnamala,
Kuwar Anil
Publication year - 2015
Publication title -
journal of molecular recognition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.401
H-Index - 79
eISSN - 1099-1352
pISSN - 0952-3499
DOI - 10.1002/jmr.2451
Subject(s) - fluorescence , aqueous solution , ion , aqueous medium , turn (biochemistry) , chemistry , pyrrole , photochemistry , materials science , organic chemistry , optics , biochemistry , physics
Cation sensing behaviour of a pyrrole‐based derivative (2‐hydroxyl 3 methyl 6 isopropyl benzaldehyde}‐3,4‐dimethyl‐1 H ‐pyrrole‐2‐carbohydrazide (receptor 3) has been explored and is found to be selective towards Zn 2+ over a variety of tested cations. The receptor 3 has shown high selectivity and sensitivity towards Zn 2+ over the other alkali, alkaline earth and transition metal ions. In the presence of Zn 2+ , absorption band of receptor 3 has shown the red shift. The sensing behaviour has been suggested to continue via enhancement process which has further been supported by UV‐vis absorption and theoretical density functional theory (DFT) calculations indicating the formation of a 1:1 complex between the pyrrole based receptor 3 and Zn 2+ . The present work is presenting a highly selective dual channel colorimetric sensor for zinc with great sensitivity. The developed sensor was successfully applied to image intracellular Zn 2+ in living cells. Copyright © 2015 John Wiley & Sons, Ltd.