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Immunohistochemical distribution of calbindin D‐28k and parvalbumin in the head of the caudate nucleus and substantia nigra of the cat
Author(s) -
De Las Heras Silvano,
Hontanilla Bernardo,
Mengual Elisa,
GiménezAmaya José Manuel
Publication year - 1994
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1052210305
Subject(s) - parvalbumin , calbindin , caudate nucleus , substantia nigra , biology , striatum , calcium binding protein , anatomy , immunohistochemistry , endocrinology , medicine , calcium , neuroscience , dopamine , dopaminergic , immunology
The heterogeneous anatomy of both the dorsal striatum at the level of the head of the caudate nucleus and of the substantia nigra of cats was analyzed immunohistochemically using two calcium‐binding proteins, namely, calbindin D‐28k and parvalbumin. The striatal histochemical markers nicotinamide‐adenine dinucleotide phosphate diaphorase and acetylcholinesterase were revealed in sections adjacent to those used for the immunohistochemical procedure. The distribution of both the calbindin D‐28k and the parvalbumin immunoreactivities is heterogeneous in dorsal, ventral, lateral, and medial areas of the head of the caudate nucleus and is in register with the striosome/matrix pattern displayed by the histochemical markers. These calcium‐binding proteins preferentially are located in the matrix compartment of the rostral caudate nucleus. Moreover, in some areas of the rostral two‐thirds of the substantia nigra, calbindin D‐28k and parvalbumin immunoreactivities appear to follow a complementary pattern that is quite different from the mesencephalic distribution of these two calcium‐binding proteins. © 1994 Wiley‐Liss, Inc.