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The interrenal gland of Triturus cristatus after insulin administration during the annual cycle
Author(s) -
LaForgia Vincenza,
Capaldo Anna
Publication year - 1992
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1052110110
Subject(s) - endocrinology , medicine , insulin , biology , epinephrine , adrenal gland , triturus , phenylethanolamine , dopamine , anatomy , tyrosine hydroxylase
The administration of insulin to Triturus cristatus confirms its action in depletion of the adrenalin (A) granules of the adrenal chromaffin cells and the subsequent activation of phenylethanolamine‐N‐methyltransferase (PNMT). Treatment was carried out in March, when noradrenalin (NA) and A granules are present in almost equal quantities in the chromaffin cells, and in June, when NA granules largely prevail. After insulin administration, adrenalin content of the specimens treated in March decreases from 2.44 granules/μm 2 to 0.28 granules/μm 2 ; on the other hand, adrenalin content of the specimens treated in June increases from 0.19 granules/μm 2 to 0.31 granules/μm 2 . These results suggest that in T. cristatus insulin acts both as an adrenalin‐releasing agent and as a stimulator of PNMT activity.