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Observations on the fine structure of the baroreceptors and adrenergic innervation of the guinea‐pig carotid sinus
Author(s) -
Shin H. S.,
Hulbert W. C.,
Biggs D. F.
Publication year - 1987
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1051940106
Subject(s) - adventitia , baroreceptor , anatomy , guinea pig , carotid sinus , ultrastructure , free nerve ending , biology , adrenergic , sinus (botany) , neuroscience , endocrinology , reflex , heart rate , biochemistry , botany , receptor , blood pressure , genus
We examined the fine structure of the baroreceptors and the adrenergic innervation of the guinea‐pig carotid sinus. The tunica adventitia contained many nerve bundles whose perineuria enclosed unmyelinated nerve fibers, alone or together with myelinated nerve fibers. Baroreceptors, which lay close to elastic and collagen fibers in the adventitia and media, were surrounded by “terminal” cells with ultrastructural features characteristic of Schwann cells and contained inclusions of various types. Morphologic features of the baroreceptors included densely packed mitochondria, osmiophilic lamellated and homogeneous bodies, clear and granular vesicles, lamellar systems, glycogen granules, neurofilaments, neurotubuli, and vacuolated mitochondria. In animals that had been treated with 6‐hydroxydopamine, occasional electrondense endings (or fibers) were observed in the adventitial layer. The baroreceptors in the guinea‐pig carotid sinus appear to have most of the morphologic features reported for other species.