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Early development of the granule cell in the cerebellum of the chick embryo
Author(s) -
Quesada A.,
GenisGalvez J. M.
Publication year - 1983
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1051780309
Subject(s) - granule (geology) , granule cell , biology , cerebellum , golgi apparatus , embryo , microbiology and biotechnology , granular layer , cell , anatomy , granular cell , cell type , biophysics , neuroscience , central nervous system , genetics , paleontology , dentate gyrus
The sequence of differentiation of the cerebellar granule cell in chick embryos from the eighth to the 15th days of incubation has been studied in Golgi‐stained celloidin sections. In the germinal‐cell phase, the presumptive granule cell sends out one or two horizontal processes which may originate either in the body of the cell or in the extension which attaches it to the pial surface. Thus the germinal cell may be converted into either a monopolar or a bipolar presumptive granular cell. Bipolar cells may have two processes of the same length (symmetrical cells) or of unequal length (asymmetrical cells). In the symmetrical as well as asymmetrical bipolar cells the leading process is formed, by means of which the perikaryon emigrates until it situates itself definitely in the internal granular layer. Thus, symmetrical and asymmetrical bipolar cells give rise to a granule cell with parallel fibers of equal or different lengths. The monopolar element may originate a second process or may remain in the monopolar phase until it reaches the internal granular layer. Once there, it completes the formation of the parallel fibers.