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Re‐regeneration of lower jaws and the dental lamina in adult urodeles
Author(s) -
Graver Heber T.
Publication year - 1978
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1051570303
Subject(s) - regeneration (biology) , blastema , biology , notophthalmus viridescens , anatomy , dental lamina , lamina , mandible (arthropod mouthpart) , cartilage , polarity (international relations) , microbiology and biotechnology , pathology , medicine , botany , genetics , odontogenic , cell , genus
Transverse amputations were carried out through one‐third fully regenerated jaw segments and through normal tissue of the mandible on the same and opposite sides of the jaw in adults of Notophthalmus viridescens . Collectively the results suggest that, in adult urodeles, the mandible and the dental lamina can be replaced in an identical manner more than one time. Although the major histological events are the same in jaw regeneration and re‐regeneration, regrowth is more rapid in re‐regeneration. Extensively dedif‐ferentiating muscle fibers and skeletal elements contribute to a rapidly forming blastema in re‐regeneration. It appears that recently differentiated tissues of the regenerate have a higher capacity for regeneration than normal tissues amputated for the first time. Re‐regeneration of the jaw occurs by growth of the original regenerate cartilage which has undergone reorganization. In re‐regeneration, the skeletal elements exhibit no polarity and regrowth occurs in both directions, while the dental lamina possesses an anterior‐posterior polarity and can regrow in an anterior direction only. Information concerning the mechanisms involved in the regenerative events remain to be determined.