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Aspects of the fine structure of the intrahepatic bile duct epithelium in normal and cholecystectomized mice
Author(s) -
Yamada Kazuyori
Publication year - 1968
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1051240102
Subject(s) - endoplasmic reticulum , biology , golgi apparatus , epithelium , cholangiocyte , gallbladder , ultrastructure , secretion , duct (anatomy) , stimulation , columnar cell , microbiology and biotechnology , ribosome , pathology , anatomy , medicine , endocrinology , biochemistry , genetics , rna , gene
The epithelium lining the intrahepatic bile ducts of normal adult mice consists of a single layer of cuboidal or low columnar cells and has ultrastructure comparable to that described previously (Rouiller and Jézéquel, '65). Some of the epithelial cells, however, exhibit such particular features as dilatation of granular endoplasmic reticulum cisternae, polysome formation of ribosomes and the presence of active forms of the Golgi apparatus, numerous lysosome‐like bodies and apical projections and blebs. Postnatal cholecystectomy does not induce any qualitative changes in the epithelial fine structure, but results in a significant increase in number of the particular structures mentioned. Therefore, the cholecystectomy is thought to stimulate the secretory activity of the epithelial cells, and such stimulation appears due to the absence of a possible activity of epithelial secretion in the gallbladder.