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Changes in the volume, form and internal architecture of the nuclei of the granular glands of the integument of the newt, Triturus viridescens
Author(s) -
Dawson Alden B.
Publication year - 1937
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1050610208
Subject(s) - biology , nucleus , triturus , anatomy , cytoplasm , secretion , apposition , cell nucleus , microbiology and biotechnology , biophysics , endocrinology
Concomitant with the appearance of the early secretion granules the nucleus enlarges slightly, the basichromatin is reduced and discrete acidophilic granules appear within the nuclei. Some nuclei become vacuolated and in others the basichromatin is practically reduced to a thin shell reinforced with occasional chromatic strands. Such nuclei are filled with acidophilic granules. In many instances the portion of the nucleus adjacent to the secretion is greatly modified, the basichromatin is reduced and presents an alveolar pattern with the alveoli filled with acidophilic material and elongated at right angles to the nuclear membrane. This appearance suggests that material is passing from the nucleus into the cytoplasm but no cytological evidence of such a passage was obtained. During the storage phase giant nuclei are present. They appear to be the result of a simple hypertrophy but in a few instances it appeared that multiplication by direct division, followed by coalescence might be a contributory factor to their formation. Following thyroidectomy or hypophysectomy the production of secretion was retarded but no profound regression was observed. After treatment with implants or injections of anterior pituitary a mild stimulation was observed. The evidence for nuclear participation in the formation of secretion is not conclusive but many of the changes which occur strongly suggest such an activity.