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The cytological changes in the hypophysis cerebri of the garter snake (Thamnophis radix) following thyroidectomy
Author(s) -
Siler Kenneth A.
Publication year - 1936
Publication title -
journal of morphology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.652
H-Index - 74
eISSN - 1097-4687
pISSN - 0362-2525
DOI - 10.1002/jmor.1050590309
Subject(s) - basophilic , biology , anatomy , histology , pathology , thyroidectomy , thyroid , endocrinology , medicine , genetics
Changes in the hypophysis cerebri of the garter snake, Thamnophis radix radix Baird and Gerard, were found in the anterior lobe of the nineteen thyroidectomized animals reported. Chromophobic cells enlarge and acquire a basophilic granulation, to become apparently normal beta (basophilic) cells. These, along with the beta cells originally present, become vacuolated, lose their granular content, apparently by liquefaction of the granules, and finally degenerate. The hypophyses of animals kept at 90°F. after thyroidectomy do not show degeneration of beta cells to the same degree that glands from animals kept at 70°F. (approximately) do. A reduction in the number of alpha (oxyphilic) cells is found under all conditions. A brief description of the morphology and normal histology of the gland is included.