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Synthesis of [ 35 S]aryl sulfonyl chlorides from [ 35 S]elemental sulfur
Author(s) -
Wallace Michael A.,
Raab Conrad E.,
Dean Dennis C.,
Melillo David G.
Publication year - 2005
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.920
Subject(s) - chemistry , sulfonyl , aryl , electrophile , reagent , sulfur , organic chemistry , combinatorial chemistry , catalysis , alkyl
A new synthetic methodology that captures electrophilic 35 S 8 with aryl Grignard reagents or lithiates provides entry to a wide variety of [ 35 S]aryl sulfonyl chlorides upon oxidation and chlorination. Copyright © 2005 John Wiley & Sons, Ltd.