Premium
Controlled synthesis of labelled 3‐ L ‐chlorotyrosine‐[ring‐ 13 C 6 ] and of 3,5‐ L ‐dichlorotyrosine‐[ring‐ 13 C 6 ]
Author(s) -
Allevi Pietro,
Olivero Paola,
Anastasia Mario
Publication year - 2004
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.882
Subject(s) - chemistry , ring (chemistry) , dichloromethane , stereochemistry , organic chemistry , solvent
Pure 3‐ L ‐chlorotyrosine‐[ring‐ 13 C 6 ] is prepared by chlorination of the 5‐oxazolidinone of L ‐tyrosine‐[ring‐ 13 C 6 ] with SO 2 Cl 2 in CH 3 COOH‐Et 2 O and successive one‐pot regeneration of the protected aminoacidic functions by BCl 3 in dichloromethane. Copyright © 2004 John Wiley & Sons, Ltd.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom