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Combining microwave‐enhanced deuteriation reactions with parallel synthesis procedures
Author(s) -
Chappelle Michael R.,
Harding John R.,
Kent Barry B.,
Jones John R.,
Lu ShuiYu,
Morgan Alan D.
Publication year - 2003
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.697
Subject(s) - chemistry , microwave , catalysis , organic synthesis , hydrogen isotope , combinatorial chemistry , solid state , hydrogen , labelling , organic chemistry , telecommunications , biochemistry , computer science
The development of combined microwave‐enhanced/parallel synthesis procedures and their application to the deuteriation of organic compounds via examples of solid‐state hydrogenation is reported. Other labelling procedures, such as solution state catalytic dehalogenations, hydrogenations as well as hydrogen isotope exchange reactions also benefit from the combined technology. Copyright © 2003 John Wiley & Sons, Ltd.