Synthesis of deuterated 4,4′‐diaminodiphenylsulfone (Dapsone) and related analogs | Zendy

Gannett Peter M. | Zendy; Johnson Edward M. | Zendy; Grimes Michael A. | Zendy; Myers Alan L. | Zendy; Deavers Robert E. | Zendy; Tracy Timothy S. | Zendy

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Synthesis of deuterated 4,4′‐diaminodiphenylsulfone (Dapsone) and related analogs

Author(s) -

Gannett Peter M.,

Johnson Edward M.,

Grimes Michael A.,

Myers Alan L.,

Deavers Robert E.,

Tracy Timothy S.

Publication year - 2003

Publication title -

journal of labelled compounds and radiopharmaceuticals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.432

H-Index - 47

eISSN - 1099-1344

pISSN - 0362-4803

DOI - 10.1002/jlcr.649

Subject(s) - sulfone , dapsone , chemistry , aniline , phenol , organic chemistry , stereochemistry , dermatology , medicine

A general scheme for the synthesis of 4,4′‐diaminodiphenylsulfone‐d 5 (Dapsone) from aniline‐d 5 is described. The method may have general application and the preparation of the related analogs, 4,4′‐dimethylaminodiphenyl sulfone from aniline‐d 5 and 4,4′‐dimethoxydiphenyl sulfone from phenol‐d 5 , is also described. Copyright © 2002 John Wiley & Sons, Ltd.

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