Premium
Synthesis and mass spectra of labelled 4(5)‐nitro‐1H‐imidazole‐5(4)‐carbonitriles
Author(s) -
Suwiński J.,
Świerczek K.
Publication year - 2002
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.607
Subject(s) - chemistry , imidazole , mass spectrum , fragmentation (computing) , nucleophilic substitution , nitro , mass spectrometry , medicinal chemistry , derivative (finance) , nucleophile , ion , nitrogen , stereochemistry , organic chemistry , catalysis , chromatography , alkyl , computer science , financial economics , economics , operating system
Abstract Cine nucleophilic substitution of 1,4‐dinitroimidazole and its 2‐methyl derivative with nitrogen‐15 or carbon‐13 potassium cyanides afforded, respectively, labelled 4(5)‐nitro‐1H‐imidazole‐5(4)‐carbonitriles. Detailed mass spectra analysis led to the conclusion that during fragmentation in mass spectrometer the labelled atoms are present in all the main fragmentation ions of m / z higher than 42. Copyright © 2002 John Wiley & Sons, Ltd.