Specific labelling of nucleosides and nucleotides with  13 C and  15 N | Zendy

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Specific labelling of nucleosides and nucleotides with 13 C and 15 N

Author(s) -

Milecki Jan

Publication year - 2002

Publication title -

journal of labelled compounds and radiopharmaceuticals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.432

H-Index - 47

eISSN - 1099-1344

pISSN - 0362-4803

DOI - 10.1002/jlcr.553

Subject(s) - labelling , chemistry , nucleoside , nucleotide , aglycone , stereochemistry , molecule , biochemistry , organic chemistry , glycoside , gene

Synthetic methods leading to nucleosides and deoxynucleosides specifically labelled with 13 C and 15 N are reviewed. The paper covers labelling the sugar part of the molecule (with 13 C) and the aglycone part (both with 13 C and 15 N). Synthetic methods for labelling at every relevant site of the nucleoside molecule are discussed. The paper also presents the strategies for the synthesis of multilabelled nucleosides. Copyright © 2002 John Wiley & Sons, Ltd.

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