Synthesis of  13 C‐labelled cinnamonitrile | Zendy

Zippi Elizabeth M. | Zendy; Kamperman Evan | Zendy

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Synthesis of 13 C‐labelled cinnamonitrile

Author(s) -

Zippi Elizabeth M.,

Kamperman Evan

Publication year - 2002

Publication title -

journal of labelled compounds and radiopharmaceuticals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.432

H-Index - 47

eISSN - 1099-1344

pISSN - 0362-4803

DOI - 10.1002/jlcr.535

Subject(s) - chemistry , acrylonitrile , nitrile , cyanide , radiochemistry , potassium cyanide , styrene , potassium , nuclear chemistry , proton , organic chemistry , copolymer , nuclear physics , polymer , physics

13 C‐labelled cinnamonitrile, a compound that possesses both the aromatic functionality of styrene and the nitrile functionality of acrylonitrile has been synthesized in one step using β ‐bromostyrene and potassium [ 13 C]cyanide. The preparation of a target material using 13 C ‐labelled cinnamonitrile may provide a cost‐effective method for producing nitrogen‐13 via proton irradiation for Positron Emission Tomography. Copyright © 2002 John Wiley & Sons, Ltd.

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