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Synthesis of [1,2‐ 14 C]trichloroacetic acid
Author(s) -
Bubner M.,
Fuksová K.,
Matucha M.,
Heise K. H.,
Bernhard G.
Publication year - 2001
Publication title -
journal of labelled compounds and radiopharmaceuticals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.432
H-Index - 47
eISSN - 1099-1344
pISSN - 0362-4803
DOI - 10.1002/jlcr.505
Subject(s) - chemistry , trichloroacetic acid , yield (engineering) , specific activity , radiochemistry , chemical synthesis , nuclear chemistry , organic chemistry , biochemistry , in vitro , enzyme , materials science , metallurgy
Abstract A growing interest in the phytotoxic effects of trichloroacetic acid (TCA) has led us to develop a small‐scale (<1 mmol) one‐pot synthesis of [1,2‐ 14 C]TCA with >70% yield and specific activity of 3.7 GBq/mmol. Copyright © 2001 John Wiley & Sons, Ltd.